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Proteins: A Mosaic Pattern to Rule Them All?

中文摘要

研究发现,氨基酸除在疏水核心聚集外,还会按化学类型以约 8 个单位为一组聚集,这一现象被称为 Mosaic Q 模型。

English Summary

Beyond the hydrophobic core, amino acids also cluster by chemical type in groups of ~8 units, a discovery called the Mosaic Q model that expands protein structure understanding.

Original Excerpt

For decades, the existence of the hydrophobic core, a region in the 3D structure of proteins where hydrophobic amino acids reside together, has been considered a general property in proteins. What we have found now may extend that model. In particular, the rest of amino acids also seem to cluster together according to their chemical type (polar, acidic, basic, special), specifically in groups of ~8 units. This is what we have come to call the Mosaic Q model. Here is how we found it, along with tools for its quantification and visualization. The post Proteins: A Mosaic Pattern to Rule Them All? appeared first on Towards Data Science.